The treatment of premature penile ejaculation begins with the treatment of its predisposing cause. Treatment methods include psycho-behavioral therapy and medication. 1. Psychological-behavioral therapy mainly aims to help patients improve their sexual self-confidence, reduce anxiety, and solve their psychological problems. This will prolong the ejaculation time. 2. Medication mainly includes oral medication, such as dapoxetine, etc.; or applying lidocaine spray locally on the glans. (1) Dapoxetine can mainly prolong the concentration of 5-HT in the central system, thus prolonging the patient’s ejaculation time. Contraindications include people who have recently had a stroke or cardiovascular disease, and people with severe hepatic or renal insufficiency. (2) Lidocaine spray prolongs a patient’s ejaculation duration by decreasing the sensitivity of the penile head. Contraindications package liver and kidney dysfunction, congestive heart failure, atrioventricular block, hypotensive shock can not be used. Once premature ejaculation occurs, you should not blindly take the drug. Should go to the hospital in time, under the correct guidance of the doctor, follow the doctor’s instructions standardized treatment.