The possibility exists that insulin function can be restored with treatment of type 2 diabetes, but there are many prerequisites for restoration of insulin function and subsequent blood glucose monitoring is still required. The approach consists of five areas: prevention, weight loss, intensive glucose reduction, metabolic surgery, and pancreas or islet transplantation. The mechanism is primarily to restore the individual’s fat threshold, release glucolipid toxicity, or improve gut hormones and gut flora so that de-differentiated insulin beta-cells regain the ability to secrete insulin. Pre-diabetes is the best time to reverse diabetes, in the pre-diabetes need to carry out lifestyle intervention, through diet and exercise therapy and other interventions to achieve the effect of weight loss, so as to improve the body’s insulin sensitivity, which promotes the transformation of pre-diabetes to normal glucose metabolism; if the effect of lifestyle improvement is unsatisfactory, you can add medication, such as pioglitazone and so on. Please follow your doctor’s instructions for medication.