It is not possible to generalize whether low blood uric acid can cause a gouty attack. Usually, the higher the blood uric acid, the higher the possibility of gout attack; however, when the patient is combined with renal disease, or is undergoing uric acid lowering treatment, etc., low blood uric acid can also cause gout attack.
1. Patients with renal diseases, such as early diabetic nephropathy, will have increased renal filtration rate, increased uric acid excretion, low blood uric acid can occur. If there are triggers such as eating a lot of high-purine food and drinking alcohol, which cause fluctuation of blood uric acid level, it will also cause gout attack.
2. When the patient is applying benzbromarone and other uric acid-lowering drugs, the patient’s blood uric acid can be reduced to a lower level. At this time, patients due to strenuous exercise, eating high purine food, etc., there can be abnormal fluctuations in blood uric acid levels, uric acid crystals may occur dissolution, or on the gout stone has been formed, causing local inflammatory reaction and gouty attacks.
Patients with low blood uric acid who experience gouty attacks are advised to go to the hospital as soon as possible and receive standardized treatment under the guidance of a specialist.