For those people who watch “Do Not Disturb 2” and rush to spot moles, I will tell them that what Li Xiangshan said is totally wrong, it is better not to spot moles casually, otherwise it may cause endless harm. I have seen many patients with melanoma because of mole spotting, and I can’t let such tragedies happen again and again. I once saw a 40-year-old woman who had a mole on her left auricle. She had the mole removed with herbal medicine at the local hospital, but the mole soon recurred and expanded in the same place, and there were some metastases. After she came to our hospital to take a pathology, she knew that it was already a malignant melanoma, and through other examinations, we also found that she had multiple metastases throughout her body. Melanoma is a malignant tumor, so it can also metastasize. The skin is very vascular and there is a high chance that the melanoma cells will be transported with the blood to other parts of the body to take root and continue their own malignant growth until more malignant cells are transported by the blood throughout the body, creating a widespread metastasis. This patient died shortly thereafter. There was also a little girl who had a mole on her chest when she was three or four years old, which was the size of a green bean and nothing special at the time. Later, when the child was almost 11 years old, her parents noticed that this mole on her body was significantly darker than before and the surface was not as smooth as before, so they took her to the local hospital for consultation and treatment. The local dermatologist said that it was a pigmented mole and could be removed by laser, so it was done with laser and left a small scar after the surgery. Unexpectedly, two or three months later, a dozen dark red papules of different sizes grew on the periphery of the original scar. Since there was no other discomfort and considering that the child was still in school, he waited until six months later before coming to us during the child’s winter vacation and was diagnosed with melanoma. After watching “Do Not Disturb 2”, many people think that the best way to prevent melanoma is to use laser to remove all the moles on the body with the idea that “it is better to kill three thousand by mistake than to spare one”. Unfortunately, this is a very wrong approach. There are two types of moles turning into melanoma, one is melanoma, but the other is that the previous moles are fine, but due to the stimulation of laser, they become melanoma due to the malignant change and spread. For normal moles, there is absolutely no need for us to burn them off with laser. Because laser is a strong stimulus for the skin, laser cauterization can remove moles and also stimulate malignant lesions in melanocytes. If you are unlucky and a mole is really stimulated by laser to become a melanoma, wouldn’t it be a mistake to kill 3,000 moles? Moreover, if a melanoma is burned with laser, the melanoma cells may fall off from the tumor, and if they unfortunately fall off into the blood, there is a chance of distant metastasis with the blood, increasing the risk of generalized development throughout the body. Although clinically, there is no data yet to suggest that the probability of malignant lesions due to laser cautery is greater than the probability of a mole naturally evolving into a melanoma, it is, after all, risky. Moreover, from years of experience, we have found that moles on children can grow slowly, especially during the child’s rapid growth period, and there may be some small changes on the body, which are not necessarily problematic. Moreover, the malignant change of moles or melanoma basically occurs after the age of 30, with the peak time around the age of 50, and children are generally unlikely to get melanoma. This is because melanoma is produced by external influences, and children are still young and do not accumulate so many negative factors, so the possibility of getting cancer is very small. The malignancy rate of melanoma is very low, so there is generally no need to worry about it. If treatment is needed, it should be surgically removed and pathological examination should be done, not freezing, laser, drug erosion and other treatments. The reasons are: ① Surgical excision is fast in recovery, does not leave scars, and has good cosmetic effect; while laser and freezing damage the surrounding normal skin, slow in recovery, and often leave scars. ②The treatment of freezing, laser and drug erosion is often incomplete, and the mole cells that have not been removed may become malignant due to stimulation. ③Pathological examination can be done after surgical excision to make a clear diagnosis, and if problems are found, they can be remedied in time, while freezing, laser and drug erosion cannot achieve this purpose. ④Early malignant melanoma looks like a “nevus” to the naked eye, and pathological examination can be done after surgical excision to make a clear diagnosis and take remedial measures. After 30 years old, new nevi rarely appear (especially the black spots on the soles of the feet). If a new “nevus” occurs and its size exceeds 0.5 cm, special attention should be paid. If a nail black line appears after the age of 30 and the pathology report has “melanocytic hyperplasia”, you should pay attention: melanoma is very likely!