OBJECTIVE: To observe the cellular morphology and cytogenetic changes during the treatment of primary and relapsed acute promyelocytic leukemia (APL) with tetrasodium tetrasulphide (TATS) and to explore its mechanism of…
Patient Question: Description: The patient is my brother, who felt unable to eat and had chest pains in February this year. After going to the hospital and finding out that…
Induction of differentiation therapy: In vitro experiments before the clinical application of ATRA have demonstrated that ATRA can induce differentiation of leukemic cell lines (e.g., HL-60 cells) and APL progenitor…
Acute promyelocytic leukemia (APL) is a specific type of acute myeloid leukemia (AML) designated as AML type M by the FAB Collaborative Group. The malignant disease of hematopoietic tissue is characterized…
I. Diagnosis of acute promyelocytic leukemia I Purpose: To establish standard operating procedures for the general diagnosis and treatment of acute promyelocytic leukemia to ensure the correctness and standardization of patient…