Irregular shedding of the endometrium is due to dysfunction of the hypothalamic-pituitary-ovarian axis. Progesterone both regulates the hypothalamic-pituitary-ovarian axis and directly affects the endometrium to make it shed intact, thus…
If irregular shedding of the endometrium is suspected, an endometrial biopsy is performed on the 5th to 6th day after menstruation and the diagnosis is made if a secretory-responsive endometrium…
The main menstrual symptoms of irregular endometrial shedding can manifest as a prolonged menstrual period (more than 8 days) and/or increased menstrual flow (more than 80 ML or more than…