Impotence should refer to erectile dysfunction (ED), and the causes of premature ejaculation include psychological factors, biological factors, etc., and the degree of difficulty in treatment will also be affected by a variety of factors, and the specific situation varies from person to person. 1. Causes: The causes of ED vary according to the type, mainly including organic, psychological and mixed 3 categories; the causes of premature ejaculation are still unclear, but most of them are believed to be the result of the interaction between psychological and biological factors. (1) ED: Organic ED: mostly related to diseases of vascular origin (e.g. penile venous fistula), endocrine diseases (e.g. hypogonadism), etc.; Psychological ED: e.g. depression, anxiety disorders; Mixed ED: can involve the various diseases mentioned above. (2) Premature ejaculation: psychological factors: such as life and work pressure, poor relationship with sexual partners, etc.; biological factors: such as abnormal hormone levels, urinary tract infection, etc.. 2. Ease of treatment: The ease of treatment for both is affected by a variety of factors, such as the cause of the disease, the individual’s physical condition, and the severity of the disease. (1) Easier to cure: caused by psychological factors and other easy to intervene, the patient is still young, good health before the disease, the course of the disease is shorter, the condition is milder, the general prognosis is good, the possibility of cure is greater. (2) More difficult to cure: caused by organic diseases, the patient is older, the basic condition is poorer, the course of the disease is longer, the condition is more serious, the general prognosis is poorer, the possibility of cure is smaller. In summary, the specific diagnosis and treatment of both diseases must be completed by professional doctors, do not blindly judge, dispose of yourself, so as not to cause adverse consequences.