Diffuse thyroid lesions are considered to be related to Hashimoto’s thyroiditis, toxic diffuse goiter, thyroid cancer, etc., which may require anti-hyperthyroidism medication, surgery and other treatments as follows: 1. Hashimoto’s thyroiditis: For patients with no obvious symptoms and normal thyroid function, regular follow-up is sufficient. If the patient is combined with hypothyroidism, it can be treated with levothyroxine as prescribed by the doctor. 2. Toxic diffuse goiter: for severe cases, anti-thyroid drugs such as propylthiouracil and methimazole can be prescribed, and beta-blockers such as propranolol can be combined to improve palpitations and other discomforts. Some patients with toxic diffuse goiter can also be treated with radioactive iodine therapy, total thyroidectomy or secondary thyroidectomy. 3. Thyroid cancer: patients with thyroid cancer can be treated with thyroxine tablets, levothyroxine tablets and other inhibitory treatments as prescribed by the doctor, and they can also have the lesions removed by surgery and have the cervical lymph nodes cleared. After surgery, patients can combine radioactive iodine therapy, chemotherapy and targeted therapy according to their conditions. It is recommended that people with diffuse thyroid lesions should undergo further detailed examination and follow the doctor’s instructions after clarifying the disease, and should not use drugs or prescriptions indiscriminately. During the treatment period, patients should pay attention to regular medical checkups, and should also pay attention to the rationality of daily diet.