Due to the rising incidence of STDs, there is a serious impact on society and families. In the STD clinic, it is common to see patients with STDs (especially those who are afraid of condyloma acuminatum and genital herpes) have symptoms of worry, fear and suspicion of disease, and they always feel that they are suffering from a lifelong difficulty in curing STDs and that they are incurable, which results in psychological and behavioral anomalies, excessive emotional tension, and a kind of mental abnormality manifestation, which seriously affects their work and life. 1, psychological abnormalities: patients suspect that they have contracted STDs, extremely afraid of STDs, and STD-related things to enhance the attention, and special attention. Slight discomfort and changes in their own bodies and even normal physiological phenomena are particularly sensitive, and that is related to STDs, is the early manifestation of STDs, pestering the doctor, repeated statements, emphasizing their symptoms, onset of the plot, put forward with STDs have nothing to do with the doubts, asking the doctor to explain. Even manifested as compulsive poor thinking, the doctor’s explanation of doubt, do not believe, and require repeated examination and treatment, showing excessive fear, worry, regret. 2.Behavioral abnormalities: highly vigilant and avoidance of sexually transmitted infections, not dare to cohabit with their spouses, self-use of washing utensils, repeated forced washing, and even cutlery, bathtubs, toilets, etc. and home isolation, and seek medical advice many times a day. 3, mental abnormality: self-sense of genital warts around the genitals, genital herpes, etc., general malaise, reduced appetite, insomnia, dare not speak with others, personality eccentricity, low self-esteem, upset, dare not interact with the surrounding people, suspected that other people look at their own in the eyes of discrimination. Some consciously have urinary incontinence, incontinence, itching and pain in the urethra, discharge, seminal emission, premature ejaculation, hypogonadism, lumbago, itching of the skin, severe cases of urethra with insect bites, the vagina has a feeling of insect crawling, many times to ask the doctor to check, but its examination, laboratory tests and no positive signs and results of STDs. Solution 1, for patients with STD phobia, need to strengthen health education, so that it maintains a balanced state of mind, scientific knowledge of STDs. 2, medical personnel should listen to the patient’s account, explanation with sympathy, understanding, sincerity and patience, and conduct detailed examination of the patient, explain to the patient in scientific and common language STD knowledge. 3, STDs are preventable and curable, doctors should explain the examination report in optimistic language and guide patients to seek medical treatment scientifically.