It is possible to cure diabetes with intensive lifestyle interventions, medications, metabolic surgery, and pancreas or islet transplantation, and blood glucose monitoring is still needed after cure, but not all diabetes can be cured, and those who cannot be cured need to adhere to lifelong glycemic control therapy. The possibility of curing diabetes exists, especially in patients with pre-diabetes. Methods include intensive lifestyle interventions, intensive glucose lowering, metabolic surgery, and pancreas or islet transplantation. However, the chances of reaching a cure for diabetes depend on a number of factors such as age, duration of the disease, blood glucose, complications, etc., and not all patients can achieve a cure. Patients who cannot be cured can be treated with glucose-lowering drugs such as metformin, acarbose, or insulin injections as prescribed by the doctor, along with dietary control and appropriate physical exercise. Although the disease cannot be cured, the prognosis is better if the blood glucose is maintained within a reasonable range. In addition, patients with gestational diabetes can control their blood glucose through dietary control and appropriate exercise, and some of them can return to normal blood glucose after the end of pregnancy without developing diabetes. Patients diagnosed with diabetes should actively cooperate with their doctors for treatment.