Blood uric acid 500μmol / L is usually more serious, need to pay great attention to, and actively lower uric acid treatment. Hyperuricemia can be diagnosed when the blood uric acid value measured more than twice on non-same day under normal purine diet is >420μmol/L. Blood uric acid 500μmol/L is elevated uric acid, which needs to be tested several times and is usually more serious. Long-term elevated uric acid may lead to gouty arthritis attacks, kidney damage, and gout stone formation. Patients should be strict low purine diet control, reduce the intake of high-fat, high-calorie, high-purine foods, such as animal offal, seafood, hot pot, beer, etc., quit drinking and smoking, increase the intake of fresh fruits and vegetables and water, and if necessary, take medication under the guidance of a doctor to lower uric acid treatment, such as benzbromarone, allopurinol, etc.. It is recommended that patients with elevated uric acid go to the hospital in a timely manner, follow the doctor’s instructions to standardize the treatment, to avoid delaying the condition.