The main treatment for PCOS is to adjust the menstrual cycle, treat hyperandrogenemia and insulin resistance, and to promote ovulation if there is a fertility requirement. Next all patients should adjust their lifestyle, control diet, exercise, quit smoking and alcohol. 1.Adjustment of menstrual cycle: Daing-35, etc., usually 3-6 months; progesterone; Didrogestrel 10mg bid po *10 days 2.Treatment of hirsutism, acne and hyperandrogenism Prefer Daing-35; 3.Treatment of insulin resistance: Metformin 500mg bid-tid 3-6 months for obesity or insulin resistance. Regular review of renal function. 4. Ovulation promotion: clomiphene, HMG, laparoscopic ovarian perforation 5. Ovulation promotion combined with artificial insemination or IVF.