1, what is polycystic ovary syndrome (PCOS) polycystic ovary syndrome is a lifelong disease affecting women, a complex and diverse endocrine disorders, accounting for 6-10% of menstrual disorders in women of childbearing age suffer from polycystic ovary syndrome, 75% of women with anovulatory infertility suffer from polycystic ovary syndrome. 2, adolescent girls or women of childbearing age encounter embarrassing problems. Why do I have acne on my face? Why do I have so much hair? Why do I gain weight even when I drink water? Why am I not getting my period? Be alert to polycystic ovary syndrome. 3, common manifestations of polycystic ovary syndrome (1) menstrual changes, menstrual sporadic (cycle 35 to 6 months), amenorrhea (cycle > 6 months), irregular menstruation, note 13% of PCOS patients with normal menstruation; (2) hairy sweat hair aggravated, especially in the thighs, arms, abdominal midline, vulva and around the anus, hair distribution has a masculine tendency; (3) acne; (4) obesity Obesity occurs in 50-60% of PCOS patients. About 15% of Chinese adults (200 million) are overweight, of which 7% (90 million) are obese, and the proportion of obesity in China is increasing in an outbreak at a rate of 30 to 50% per year, and Chinese people are more inclined to have metabolic diseases at a lower BMI level. 4, the impact of polycystic ovary syndrome (1) the impact of PCOS – adolescence menstrual disorders, acne and obesity, increase the psychological burden of adolescents, but also increase the occurrence of infertility and other diseases in childbearing age. (2) Effects of PCOS – Reproductive age The rate of conception decreases, and PCOS in reproductive age often leads to abnormal ovulation due to endocrine disorders, thus causing infertility. The rate of miscarriage increases: the incidence of spontaneous abortion in the third month of pregnancy in women with PCOS is as high as 30% to 50%, three times that of women of normal childbearing age, and 36% to 82% of women with repeated early spontaneous abortions suffer from PCOS. endometrial hyperplasia, endometrial cancer incidence increases: the incidence of endometrial cancer in patients with PCOS is four times that of the normal population. (3) Effects of PCOS – Pregnancy Increased incidence of gestational diabetes, hypertension, obstructed labour, low birth weight or large babies, congenital birth defects, fetal death or neonatal death. hyperandrogenemia in PCOS also has adverse effects on the development of the offspring. Studies suggest that improving the hyperandrogenemia and hyperinsulinemia status of pregnant women with polycystic ovary syndrome during pregnancy has a beneficial effect on the ovarian function of their female offspring. Obese women are at increased risk of having children with autism or developmental delay, with a 67% increased chance of having a child with autism than a normal weight mother. (4) Effects of PCOS – old age In patients with PCOS in old age, although there is no longer a requirement for fertility, patients with polycystic ovary syndrome are prone to diabetes and cardiovascular disease, so these patients must still be followed up to prevent diabetes and cardiovascular disease. We should pay attention to patients with polycystic ovary syndrome to achieve early detection and early treatment. This can reduce infertility, pregnancy complications, and thus greatly reduce the incidence of perinatal mortality and birth defects, as well as prevent long-term complications such as endometrial cancer, type 2 diabetes, and cardiovascular disease.