Vitiligo is a common and frequent pigment loss disease. The cause of the disease is summarized in nine factors: genetic factors; psychoneurological factors; chemical factors; tyrosine, copper ion relative lack of factors; infection factors; trauma factors, etc. The disease is characterized by local or generalized pigment loss to form white spots, is a kind of acquired limited or generalized skin pigment loss disease, although not painful, but erosion of the patient’s healthy skin and mind, serious damage to human appearance, frustration The person’s spirit, affecting normal life, marriage, work and social life.