KI67 suggests an increased regional value-added index and is meant to represent active tumor proliferation. Ki67 is a nuclear protein usually used in immunohistochemical reports of pathology.The expression level of Ki-67 often predicts the degree of active cell proliferation. In the pathology report, the higher the Ki67 expression level, the more active cell proliferation, the higher the degree of malignancy, and the more likely to recur and metastasize. If the value of Ki67 is lower than 15%, it indicates that the cell proliferation is very inactive, and it is not easy to have recurrence and metastasis. Generally speaking, the lower the Ki-67 index, the slower the cell proliferation, the lower the degree of differentiation, the better the prognosis. On the contrary, the higher the Ki67 index, the faster the cell proliferation, the lower the degree of differentiation, the higher the degree of benignity, and the worse the prognosis. The higher the regional proliferation index of KI67, the more active the tumor proliferation and the higher the degree of malignancy. Therefore, it should be actively treated in regular hospitals. If KI67 reaches 80%-90%, you can strive for a smaller lesion before surgical resection through regular treatment.