Total yawning, sleepiness, and lack of energy can be seen in patients with sleep disorders. Due to a long period of little sleep or poor sleep quality, resulting in chronic lack of oxygen in brain cells, it can manifest as total yawning, sleepiness, and lack of energy, and in severe cases, it can also be accompanied by poor concentration and memory loss. In this case, it is recommended that sleep adjustment is the main focus. Yawning, sleepiness and lack of energy can also be caused by organic diseases, such as metabolic encephalopathy, more commonly known as Hashimoto’s encephalopathy and toxic encephalopathy, such as carbon monoxide poisoning or heavy metal poisoning, which can lead to a lack of oxygen in the brain cells of the patient. In this case, the original disease should be actively treated, and if necessary, the patient can be given symptomatic treatment such as hyperbaric oxygen.