Acne, which in medicine we call acne, is a chronic inflammatory disease that involves the sebaceous glands of hair follicles. It is most likely to occur on the cheeks and forehead, followed by the chest, back and shoulders, and is mostly symmetrical in distribution, often accompanied by seborrhea. It can affect people of all ages, but has the highest incidence in adolescence. After adolescence, most of the patients have their symptoms reduced year by year or healed naturally. In recent years, as the pace of life accelerates, the pressure of life increases and environmental pollution intensifies, the incidence of this disease is on the rise, seriously reducing the quality of life. In fact, acne is a multifactorial disease, and the reasons why acne develops cannot be generalized. The development of acne is related to many factors, including increased androgen levels, excessive sebum secretion, abnormal keratinization of the sebaceous ducts of hair follicles and bacterial infections in the hair follicles. On the one hand, men and women in adolescence are in a period of vigorous physical development, so all body organs are constantly developing, and the secretion of androgens, which affect physical development, is accelerated. On the other hand, young people in adolescence are very energetic and their sebaceous glands secrete excessively. Excessive oil accumulates in the pores and leads to the blockage of the hair follicles, creating an anaerobic environment that is conducive to the proliferation of Propionibacterium acnes and other bacteria, which is another important reason for the occurrence of acne. In addition, the onset of acne in adolescents is not only related to the environment and genetics, but also to factors such as high pressure from studies and employment, high-fat and high-sugar diets, frequent use of Internet equipment, high mental tension, and irritability. Therefore, acne can occur at any age, but the incidence is highest during adolescence.