Closed acne is a type of lesion in early acne. It is mainly formed when the follicle sebaceous gland opening is blocked by keratinization and the sebum contents cannot be discharged and accumulate locally. Closed acne on the cheeks can be cleared with tools or topical medications, using methods such as chemical peeling.1. Acne removal: To be performed under strict sterilization conditions, the procedure is operated by a dermatologist, who uses a needle to pierce the epidermis of the acne site and squeeze out the contents. After removal, local sterilization is performed, and red and blue light can be used, which can kill bacteria and enhance the production of elastin and collagen. Patients are not recommended to operate on their own, which can easily cause bacterial infection and local tissue redness and inflammation; 2. Topical medication: such as vincristine cream, adapalene gel, tazarotene gel, etc. These medications can promote the keratinization of the follicle opening to loosen the acne contents. It is usually recommended that vincristine should be used away from light. After use, there may be local irritation, redness and itching, and the next day, emollients can be used topically to reduce the irritation symptoms; 3. Chemical peeling treatment: With the method of chemical peeling with fruit acids or salicylic acid, fruit acid peeling will accelerate the metabolism of the stratum corneum and facilitate the smooth opening of the sebaceous ducts of hyperkeratotic follicles, and by accelerating epidermal renewal, the treatment of The purpose of closed acne is achieved by accelerating epidermal renewal.