Excessive secretion of sebaceous glands: Hormone level imbalance (relatively high androgen level before puberty and female menstruation), except for patients with polycystic ovary syndrome, most patients have estrogen and androgen levels within the normal range; excessive stress (including stress, exams, poor sleep, staying up late); diet of spicy and stimulating and greasy foods can lead to increased secretion of sebaceous glands. Countermeasures: It is recommended to use cleansing milk, oil control skin care products, prohibit spicy and stimulating, greasy food, and have a regular life. Severe patients can take oral retinoids, female patients can take Dain 35, or use Chinese medicine for evidence-based treatment. Hyperkeratosis of hair follicle sebaceous gland ducts, forming keratin plugs to block pores. Countermeasures: Pay attention to the cleanliness of the skin and take oral or topical retinoids. P. acnes colonization: The keratinous plugs formed by the blocked hair follicle opening are very conducive to the reproduction of P. acnes bacteria. Inflammatory response: Acinetobacter can break down triglycerides into fatty acids, stimulating an inflammatory response in the surrounding skin, leading to the formation of inflammatory papules and pustules, cysts and nodules. Countermeasures: Oral antibiotics, topical anti-inflammatory drugs and intensive care products can be used for obvious inflammation. Those with obvious scars can be treated with topical scar removal products, laser treatment or surgical grinding.