Research has found that about 1/3 of cancers can be prevented British scientists have found that even if you are usually in good health, it is very likely that a sudden “big bang” of a cell will cause you to develop cancer very quickly! Is cancer really impossible to prevent? No. According to experts, as we learn more about the molecular mechanisms of tumorigenesis, we will be able to further increase the efficiency of cancer prevention and treatment. Moreover, authoritative clinical medical research has long been confirmed: about 1/3 of the cancer is completely preventable; internal medicine treatment can now cure some tumors. 1, only 1/40 cancer will break out overnight I just heard that a friend was hospitalized with nasopharyngeal cancer, and I was shocked! When I saw him a few days ago, he was still red-faced, full of energy, joyful, a healthy demeanor, how suddenly he suffered from cancer? Is he suffering from “instant cancer”? He is still suffering from traditional cancer, that is, the damage to the chromosomes is the result of accumulation over the years. What is “instantaneous cancer”? The Daily Mail reported on January 7 that scientists at the Sanger Institute in the UK found that some chromosomes appear to be damaged overnight after studying genetic defects in tumors. “Inside a cell, chromosomes become fragmented after one or more explosions. At this point, the cell tries to rebuild the unreconstructable chromosomes, working to put them back together, and ends up creating a catastrophic, cancer-forming genome that greatly shortens the cancer process.” This latest discovery explains “why a person who showed no signs of abnormality in a checkup not long ago is diagnosed with a highly spreadable cancer a few months later.” Such “acute cancers” are particularly common in bone cancer. It’s not certain what causes this chromosome “explosion,” but suspected culprits include X-rays and sunburn, the researchers said. Moreover, such tumors that do not fit the “standard pattern” account for only about 1/40, while the vast majority of cancers are the result of “slow development”! 2, the rapid replication of cancer has a stage Why that friend suffering from nasopharyngeal cancer, the past physical examination is good, but now suddenly occurred cancer? Experts explain: the reason why cancer makes people have the feeling of sudden arrival is that the rapid replication of cancer has a stage. Cancer cells are abnormally proliferating cells caused by a genetic mutation. By monocloning, one becomes two, two becomes four, and dividing at different multiplication times, the cancer cells keep increasing. At the beginning, it will not grow freely and frantically without any limitation. When the number of cancer cells reaches a certain number and the cancer tumor reaches a certain degree, its multiplication speed slows down under the inhibition of the “negative feedback mechanism” of the organism. Moreover, the cancer cells replicate rapidly, the cancer tumor grows too fast, and the nutrition cannot keep up with it, it needs to build new capillaries, and recuperate energy, and when it has enough energy for growth, it will start a new stage of rapid growth. When the cancerous mass grows to a certain extent, under the inhibition of “negative feedback mechanism”, it slows down the multiplication speed and starts a new period of energy conservation. In this way, the cancerous mass develops one stage after another until it grows enough to escape from the “negative feedback mechanism” of the organism and develops unchecked. If the diameter of the lump is still too small to be detected during a certain medical checkup, people think they are still healthy; after a period of time, after several times of multiplication, the lump is so big that it can be detected by modern sensitive examination, or the clinical symptoms of cancer appear, patients will immediately feel that bad luck suddenly falls from the sky! 3. There will be signs and symptoms during the latent period. My friend, who is a doctor, inadvertently touched a small, painless lymph node lump on the neck below the ear root and knew that it was not good, so he went to the hospital immediately for examination and was diagnosed with nasopharyngeal carcinoma. Because of the lymph node metastasis, the cancer may have reached the middle or late stage! In the long latent period of cancer, are there no signs to show? It should be said that there are, especially the superficial ones, whose changes can still be seen. 4. Cancer has 3 stages of development (1) Initiation stage The initiation of cancer refers to the cells under the action of carcinogenic agents, which cause certain irreversible changes (mutations) in the cell genome. Mutated genes, including precancerous genes and tumor suppressor genes, etc.. What genes are more prone to mutation? This is related to genetic factors. Mutations in key genes are the initiating events that lead to the development of cancer. Initiation can also be caused by very low doses of carcinogens to which people are generally exposed. Therefore, initiating cells are often produced spontaneously or induced in the body. Initiating cells are not cancer cells… However, they are different from normal cells in that they cause tumorigenesis when stimulated by “promoters”. (2) Promoter phase Promoters act on tumorigenesis by stimulating “cell proliferation” rather than “inducing mutations”. It has no, or only very weak, carcinogenic effect, but repeated use can increase cell division, so that the initiating cell produces the proliferating cell population needed in the early stage of tumorigenesis, and can form benign tumors. Studies of skin cancer in mice have shown that although carcinogens can cause mutations and initiation, tumors do not occur until after the use of the promoter, fobol ester, the mutated cells proliferate and then grow tumors. Frequent exposure to a variety of promoters, such as certain foods, hormones and exogenous chemical promoters, their effects can be additive, causing clonal expansion and abnormal differentiation of the initiating cells, thus causing cancer. (3) Progressive Stage The progression of cancer is the process of transformation from a benign tumor to a malignant tumor and further evolution to a tumor with a more malignant phenotype. When the repair mechanism of DNA damage and gene mutation is defective; or the structure of pre-oncogenes, tumor suppressor genes, or cell cycle regulator genes is altered, etc., the cancerous transformation of cells enters into the progression stage. In the process of progression, there are often other gene mutations in the tumor cell population, such as “faster growth” or “invasive and metastatic characteristics”, which make the tumor grow more rapidly and become more malignant. 5. Prevention: Keep away from “promoters” Genetic factors are given by parents, we can’t change them; environmental pollution hides killing opportunities, which can’t be prevented, we can’t completely eliminate the possibility of “cancer” initiating in the organism, what should we do? At present, the most possible way to control the development of cancer is to stay away from promoters during the “promotion period”. Many synthetic and natural chemicals, such as peptides, steroid hormones and growth factors, will change the characteristics of gene expression, or stimulate cell reproduction, or inhibit apoptosis, and play the role of tumor promoters. 6.Prevention: Everyday good mood What is the relationship between cancer and stress? Expert introduction: The “negative feedback mechanism” we mentioned above is directed by the central nervous system. Research has found that the three major systems of nerves, endocrine and immune systems share some chemical signaling molecules. The three systems to these common “chemical signaling molecules” as a common language, for regular information exchange, the cerebral cortex on the “information” for integration, once found where there is an abnormal phenomenon, such as cell overgrowth, will mobilize the negative feedback mechanism for inhibition. Stress and other mental factors can lead to cancer through the role of the nervous system, resulting in “neurological, endocrine and immune” mediation dysfunction. Should people in their 50s and 60s be aware of the early signs of cancer? Of course, it is even more important to stay away from “cancer promoters” at a young age!