Both ibuprofen suspension and suppositories are composed of ibuprofen, which is a non-steroidal anti-inflammatory drug that inhibits the synthesis of prostaglandins, thus exerting an antipyretic and analgesic effect. Both are suitable for reducing fever in children aged 6 months to 12 years, and both have better antipyretic effects. However, in comparison, the onset of action of the suspension is faster. Since suppositories are made of drug and suitable matrix, the onset of action is slightly slower than that of oral administration, but with the extension of time, the absorption of suppositories increases and blood concentration gradually rises, which can also achieve similar cooling effect as that of suspension. Although ibuprofen suspension and fever suppositories have the same ingredients, there are still some differences in their use due to different dosage forms. Specific: 1. Compliance: Ibuprofen suspension has a good taste and children are more cooperative when taking it. However, if children have febrile convulsions or vomiting and other reasons that prevent them from taking the drug orally, they can choose suppositories at this time. 2, adverse reactions: ibuprofen itself has fewer side effects and is safer, but there is still the possibility of stimulating the gastrointestinal tract, and very few patients can produce liver and kidney damage. The absorption of suppositories is only through the intestinal mucosa, which does not stimulate the gastrointestinal tract, so the possibility of adverse reactions is much smaller.