Children with otitis media with fluid in the tympanic cavity can follow the doctor’s instructions to take antibiotic and glucocorticoid medications. Children with otitis media may be treated with surgery if necessary. Children with otitis media with fluid in the tympanic cavity can be treated with antibiotics, such as cefuroxime and cefradine, if they are in the acute stage of infection. Some children with otitis media, also accompanied by significant pain, edema, can be further given glucocorticoid drug therapy, such as dexamethasone and so on. In addition to the above medications, children with otitis media can be treated with hydroxymetazoline hydrochloride if the otitis media triggers excessive fluid buildup within the tympanic cavity, which further induces symptoms such as nasal congestion. When there is more fluid in the tympanic cavity and the effect of conservative treatment with drugs is not good, tympanocentesis, tympanotomy, etc. are needed to help the drainage of pus. Regarding the specific medication for children with otitis media with fluid in the tympanic cavity, as the severity of the disease varies, there is also variability in the use of medication, it is recommended to consult a specialized doctor.