There is no such thing as “the best treatment for diabetic foot numbness”, diabetic foot numbness may be caused by diabetic peripheral neuropathy, diabetic foot and other diseases, which need to be targeted treatment on the basis of lowering glucose, such as medication, surgery and so on. 1. Diabetic peripheral neuropathy: there may be sensory abnormalities in the lower limbs, such as numbness, ant walking sensation, etc.; available nutritive drugs, such as vitamin B12. 2. Diabetic foot: there may be symptoms such as lowering of foot temperature, pain, numbness, etc. Nutritional nerves and vascular protection drugs can be used for treatment; in serious cases, surgical treatment can be considered, such as endoluminal intervention of lower limb arteries and vascular bypass surgery. 3. Glucose-lowering treatment: diabetic patients should also follow the doctor’s instructions to take acarbose, metformin and other glucose-lowering drugs or injections of insulin therapy, with dietary control, appropriate exercise, blood glucose control within a reasonable range. Diabetic patients with symptoms of numbness of the feet should go to the hospital, ask the doctor to make a judgment and develop individualized treatment.