Adjuvant treatment of breast cancer with bioimmunotherapy can improve the quality of survival and prolong the life span of breast cancer patients. Bioimmunotherapy, by collecting a small amount of peripheral blood from patients and obtaining more efficient and specific anti-tumor specific killer cells (DC cells, CIK cells, etc.) through in vitro isolation and culture, after culturing and adding value in the laboratory, and then transfusing back to patients in stages, can kill tumor cells, regulate and enhance the immune function of the body without damaging the structure and function of the body’s immune system. It can prevent tumor recurrence and improve the survival quality of patients with advanced disease. Biological immunotherapy is a new tumor treatment method, and the use of autologous cellular immunotherapy for post-surgical tumor patients can remove the scattered tumor cells in the body and prevent the recurrence and metastasis of many kinds of tumors after surgery; the use of biological immunotherapy for consolidation treatment for tumor patients in the recovery period can control the metastasis and recurrence of tumor cells, enhance immunity, and improve the patient’s quality of life and improve the patient’s survival. For advanced tumor patients, if patients’ personal constitution cannot bear the side effects of radiotherapy treatment, they can choose the less painful bioimmunotherapy, which is almost painless and effective in the treatment process.