Vaginal dryness after total hysterectomy is considered to be caused by the decrease of estrogen level, or it may be caused by premature ovarian failure, dry syndrome and other diseases, which need to be treated according to the cause. 1. Reduced estrogen levels: reduced levels of estrogen in the body after total hysterectomy can lead to vaginal dryness, the patient can take oral estrogenic drugs under the guidance of the doctor, such as estradiol benzoate, estradiol valerate, and so on. Or apply estrogen ointment such as estradiol benzoate ointment and estradiol gel locally as prescribed by the doctor. 2. Premature Ovarian Failure: Premature Ovarian Failure is considered to be related to viral infection, surgical damage to the ovaries, heredity and other factors. Patients will have vaginal dryness, difficulty in sexual intercourse, decreased libido and other manifestations. If the patient’s ovaries are damaged during total hysterectomy, it may lead to vaginal dryness. Long-term estrogen and progesterone replacement therapy is needed under doctor’s guidance. 3. Dry syndrome: The cause of dry syndrome is not yet clear, and it is considered to be related to infection, heredity and abnormal immune function. Patients will have a decrease in secretion of vaginal mucosal glands, resulting in vaginal dryness. If patients with total hysterectomy have dry syndrome, it will be manifested as vaginal dryness. Medications, such as bromhexine hydrochloride, need to be administered under doctor’s supervision. There are many other reasons for vaginal dryness after total hysterectomy, patients should consult a doctor in time to check the cause of the disease, and the doctor will take appropriate measures to treat the cause of the disease.