Vaginal dryness in middle-aged people can be treated with estriol ointment or oral tibolone tablets and estradiol drospirenone tablets. Vaginal dryness in middle-aged people is mainly due to the fact that after menopause, the amount of estrogen, progesterone and other hormones in the body decreases, causing a decrease in the amount of vaginal secretions, resulting in the appearance of dryness, which is a relatively common situation. It is generally recommended to apply estriol ointment to the vagina for localized treatment, to enhance its internal estrogen secretion, so as to improve the dryness problem. If the situation is relatively serious, the effect of external drugs is not good, you can also take oral tibolone tablets, estradiol drospirenone tablets and other drugs to regulate, stimulate the body to secrete more hormones, thus helping to improve all kinds of vaginal, physical discomfort. Vaginal dryness in middle-aged people is still a big impact on sexual life, it is recommended that under the guidance of a doctor to choose the appropriate medication for treatment.