Ventricular septal defect (VSD) is the most common form of congenital heart disease, accounting for approximately 20% of the total incidence of congenital heart disease. Since VSD can lead to complications such as recurrent respiratory infections, growth retardation, pulmonary hypertension and infective endocarditis, treatment is advocated for VSDs with clinical symptoms or those that do not heal spontaneously. In recent years, with the improvement of interventional devices and the maturation of technical methods, the success rate has increased significantly and the complications have been reduced. It has been clinically reported that for some peri-peripheral VSDs, in addition to the conventional VSD blocker, the PDA blocker or spring ring can be selected for blocking according to the location, size and morphology of the VSD, with a high success rate and fewer complications. Recently, a new type of Duct Occluder II has been used in our hospital to try to occlude small VSDs in the perimembranous region of young children, with good results and few complications, as described below. VSD has a high prevalence in congenital heart disease, and because it has a certain rate of self-healing – especially in infants and children – there has been controversy about when to take treatment in this group of children. If the VSD is large and affects the growth and development of the child, or causes recurrent respiratory infections and heart failure, early intervention is recommended; for smaller VSDs, outpatient follow-up is possible, but if the follow-up reveals no possibility of self-healing, treatment is recommended, which can be divided into surgical and medical interventions. Secondly, medical interventions such as improper selection of blocking devices can affect the closure of aortic valve and tricuspid valve and cause postoperative regurgitation. Therefore, there are various choices of devices for pmVSD intervention, such as perimembranous eccentric umbrella, symmetric umbrella, zero-sided umbrella, small-waisted large-sided umbrella, etc., all of which require clinicians to choose appropriately according to the morphology and location of the child’s VSD; some physicians even choose PDA mushroom umbrella and spring ring for blocking according to the special morphology of VSD, and the results are still better without significant complications.