Severe hypertension, which means that the patient is currently a tertiary hypertensive, is a condition that must be treated with active intervention to avoid adverse events. Patients are advised to take oral antihypertensive drugs and one of these antihypertensive drugs is a diuretic, such as hydrochlorothiazide tablets. In addition, patients are advised to take oral calcium channel blockers and angiotensin-converting enzyme inhibitors, with representative drugs such as nifedipine, felodipine, amlodipine, perindopril, and benazepril. If the blood pressure still cannot reach the standard after the combined application of the above three categories of drugs, we must find out whether there are abnormalities in the patient’s blood sugar. For people with obesity or insulin resistance, refractory hypertension often occurs, and blood sugar must be regulated at the same time as lowering blood pressure, and it is possible that blood sugar will be stabilized and the condition of severe hypertension will be better corrected. Patients are advised to have a low-salt, low-fat diet, regular work and rest, keep a happy mood, and lifestyle interventions to improve are also essential.