Diclofenac sodium is a non-steroidal anti-inflammatory analgesic with therapeutic effect on joint, muscle and bone pain caused by various reasons, but it is not a narcotic analgesic. Diclofenac sodium is a non-steroidal anti-inflammatory analgesic, and its mechanism of action is to inhibit the release and activity of inflammatory factors, thereby reducing pain, and thus has both anti-inflammatory and analgesic effects. Diclofenac sodium is one of the stronger non-steroidal anti-inflammatory drugs, which is generally absorbed quickly after oral administration and mainly metabolized by the liver and excreted by the kidney. It is mainly used for the treatment of joint, muscle and bone pain caused by various reasons, such as acute and chronic rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, frozen shoulder, bursitis, tendonitis and tenosynovitis, soft tissue sprain and contusion, gouty arthritis, sprain, strain and other soft tissue injuries. In addition, diclofenac sodium is also effective in women with dysmenorrhea or adnexitis, toothache and post-operative pain. Diclofenac sodium also has gastrointestinal, cardiovascular and other adverse effects, which need to be taken into account when using it, and the liver and kidney functions should be reviewed regularly. Therefore, diclofenac sodium is a more commonly used non-steroidal anti-inflammatory painkiller, the dose and frequency of its use need to be determined according to the type of disease suffered, the severity of pain and the patient’s general condition, under the guidance of a doctor, and should not be taken at will.