Rheumatic diseases are a group of diseases of the immune system that affect bones, joints and their surrounding soft tissues, such as muscles, bursae and fascia. It includes many kinds of diseases, such as rheumatoid arthritis, ankylosing spondylitis, dry syndrome, polymyositis, dermatomyositis, systemic lupus erythematosus, osteoarthritis, reactive arthritis, scleroderma, etc., all belong to the scope of rheumatic diseases, the most common of which is rheumatoid arthritis. Rheumatic disease is not a disease that simply damages joints; it is a systemic disease that can cause damage to a person’s lungs, heart, kidneys, nerves, eyes, etc. One of the more common rheumatic diseases is ankylosing spondylitis, a chronic inflammatory immune disease that involves the spine and is an important cause of human disability. The age of onset is mostly 16-40 years old, with a higher prevalence in men than in women. The clinical presentation is low back pain, followed by back pain and back stiffness, and eventually deformities of the spine such as hunchback and neck ankylosis. In addition, patients with ankylosing spondylitis can develop eye disease and damage to organs such as the kidneys. In addition to the onset of rheumatism after exposure to wind and cold or rain, many patients also suffer from prolonged exposure to cold and shade, trauma, and frequent intestinal infections. Of course, not all patients will develop rheumatism after being exposed to wind and cold, which is related to each person’s physical condition, age, gender, genetic factors, endocrine and metabolism. For example, some patients start with pain in a single joint, such as the elbow joint or wrist joint, and then gradually develop into symmetrical pain in two joints, from a large joint to a small joint pain. This also suggests that we should not think that rheumatoid arthritis is only a problem of symmetrical pain in small joints, and that when joint pain occurs, we should go to a specialist in a timely manner.