Rheumatic diseases belong to a large group of diseases, a wide variety and mostly chronic diseases, is due to the joints, bones, muscles, blood vessels and soft tissues by the invasion of the disease, can cause joint, bone, muscle pain, swelling, activity restrictions, etc.. Such diseases are mostly considered to be related to genetic factors, environmental factors, infection factors, as well as the patient’s own immune factors, endocrine factors: 1, genetic factors: it is widely believed that rheumatism has certain hereditary factors, many patients with such diseases have a clear, aggregated history of rheumatism in the family parents or other elders; 2, environmental factors: the concept of Chinese medicine that wind, cold, wet are causative factors of rheumatism In the case of cold, dark and humid outdoor work, such as fishing, cold storage, washing clothes and other work content, cold and damp into the body, more likely to suffer from rheumatic diseases; 3, infection factors: specific infection is also an important cause of rheumatism, such as Salmonella spp, Shigella fowleri, Helicobacter pylori and other infections; 4, immune factors: it is generally believed that in the genetic factors and environmental factors The joint action of genetic and environmental factors, the patient’s immune function will be abnormal or damaged, eventually leading to the occurrence of autoimmune diseases, making patients appear ankylosing spondylitis, rheumatoid arthritis, and systemic lupus erythematosus and other rheumatic diseases; 5, endocrine factors: this situation is mostly seen in female patients, some clinical trials that estrogen will promote the occurrence of rheumatoid arthritis, while progesterone can reduce the disease, all suggest that Rheumatic disease and endocrine factors. Therefore, such as female patients with systemic lupus erythematosus, rheumatoid arthritis and other diseases, endocrine factors should also be considered.