Lipomas of the hand are mostly benign tumors. Lipomas that occur in the hands are mostly benign. Lipomas are relatively common benign soft tissue tumors that grow slowly and are more common in middle-aged people. They grow under the skin and are called superficial lipomas. Lipomas on the hands are superficial lipomas. If they do not affect the patient’s daily life, they do not need to be treated. It is important to observe and detect the lumps in daily life and have regular checkups. If the tumor is large and has caused local pressure, pain, dysfunction and other symptoms, or affects the aesthetics, then surgery can be chosen to remove it. Generally speaking, lipoma of the hand is rarely malignant, and the prognosis is good after surgical removal.