Lipoma is a relatively common tumor in human body, the etiology is unknown, a few patients have family history, most scholars think that it is related to inflammation or due to the obstacle of lymphatic supply and blood circulation of tissues, resulting in the deposition of adipose tissues, and some people think that the onset of the disease is related to the congenital dysplasia and the obstacle of systemic fat metabolism, but the evidence is still insufficient. Most common in middle-aged people, is originated from the adipose tissue of a benign tumor, any part of the body can occur, some multiple, more than dozens of hundreds, but rarely malignant changes. Clinically, it commonly occurs under the skin of shoulder, back, abdomen and buttocks. Smaller lipomas that develop slowly without clinical symptoms usually do not require treatment. However, if some of them grow fast, or some of them have grown so big that they feel pain or affect function and aesthetics, surgical excision can be considered. Currently there is no effective drug treatment, but can be prevented by paying attention to the general life: do not eat alcohol or drink less alcoholic beverages, eat a regular diet, eat a good breakfast, a low cholesterol diet is very important, a high cholesterol diet will cause excess cholesterol to accumulate in the subcutaneous area, which will easily lead to the formation of lipomas.