Recently, 50-year-old Mr. Liu had a headache in his right ear and went to the hospital to see Dr. Wang. Mr. Liu told me that when he was 10 years old, he had pus in his right ear, and at that time his family was poor, so he saw a country doctor and bought some medicine, and then he had pus in his right ear for more than 1 year, and then he slowly stopped having pus, and then he had pus 3-4 times, and then he was fine after using medicine. 3 days ago, Mr. Liu was working at a construction site and suddenly he had a headache on his right side, so he was sent to the annex clinic by a colleague. The physician gave Mr. Liu an anti-inflammatory injection, which was better when he was hanging, but when he returned home, the headache started again. The doctor gave Mr. Liu an endoscopic examination and found that Mr. Liu’s eardrum was sunken and there was a small hole in the upper part of the external ear canal. The doctor sucked out a lot of pus from this small hole and then told Mr. Liu that it might be a recurrence of middle ear infection. Mr. Liu followed the doctor’s advice and was hospitalized for otitis media lesion removal surgery, and was fitted with an artificial auditory tuberosity. After the surgery, Mr. Liu’s headache disappeared and his hearing in the right ear improved significantly compared to that before the surgery. What are the diseases that can cause pus in the ear? Otitis externa, mycobacteria of the external ear canal, tumors of the external ear canal and chronic otitis media can all cause pus in the ear. What should I do if I have pus in my ear? Some are infections of the external ear canal, some are infections of the tympanic membrane perforation, and some are infections of the bone behind the ear (mastoid process). Some do not have pus flowing from the ear as a sign of improvement, but some have the tympanic membrane perforation blocked and the pus in the bone behind the ear slowly spreads to the skull (brain), resulting in intracranial infections, which can cause stagnant reactions in mild cases and life-threatening ones in severe cases. Doctors remind patients that it is best to see a doctor and to see an otolaryngologist.