Vaccine-induced thrombocytopenic purpura may be true, but there is no clinical evidence to support it. Vaccines are special medicines, which may have certain toxicity. After the body is injected with vaccines, it may be affected by the medicinal properties or toxicity of the vaccines, which may cause thrombocytopenic purpura. This kind of thrombocytopenic purpura mostly belongs to secondary thrombocytopenic purpura, which may have various symptoms such as bleeding, thrombocytopenia, and infection. Thrombocytopenic purpura symptoms occurring in the body after vaccination need to be considered vaccine-related. However, there is insufficient clinical data to support a correlation between vaccination and the occurrence of thrombocytopenic purpura. The symptoms of thrombocytopenic purpura can be controlled with glucocorticosteroids such as prednisolone and, if necessary, platelet transfusions when bleeding is more severe. The use of medication should be directed by a doctor. After vaccination, it is important to pay attention to physical symptoms. If there is any discomfort in the body, such as the presence of symptoms of thrombocytopenic purpura, patients are advised to go to the hospital for treatment in a timely manner.