A small number of renal types of purpura may develop into end-stage renal disease, which has a poorer prognosis and affects life expectancy; other types are generally unaffected.
Anaphylactic purpura is common in children and adolescents, with a higher incidence in spring and fall. The main clinical manifestations include skin purpura, abdominal pain, proteinuria, hematuria, joint and periarticular swelling, pain and tenderness, and neurologic symptoms. After systematic and standardized treatment, most cases, especially children’s cases, can recover within half a month, and most of them have a good prognosis.
A few patients with renal phenotype can develop progressive renal impairment, and very few of them can also delay for months or even years, and finally develop chronic nephritis, nephrotic syndrome or even end-stage renal disease, which has a poorer prognosis and may affect life expectancy.