Thrombocytopenia splenectomy does not help, considered refractory thrombocytopenic purpura, can take rituximab, androgens and cyclosporine and other drugs, may also be acute leukemia, etc., need to be treated by specialists.
1. Although splenectomy is effective in treating immune thrombocytopenic purpura, with about 60% of patients in remission after splenectomy and a sustained remission rate of more than 30%, there are many cases of failure and even relapse.
If it is ineffective or recurs after splenectomy, it is considered refractory thrombocytopenic purpura and needs to be reevaluated and treated with targeted drugs such as rituximab if necessary. Within six months of drug therapy, attention needs to be paid to whether the patient is immunocompromised or not.
Thrombopoietic drugs such as androgens (testosterone) can also be used, with milder adverse effects, such as fever and muscle pain seen.
Immunosuppressants are also an option for the treatment of refractory immune thrombocytopenic purpura, such as cyclosporine.
2. In addition, thrombocytopenia can also be seen in a variety of diseases, such as acute leukemia, which requires specialist treatment with drugs such as cytarabine and zithromax.
In addition, drugs such as Eltrombopag, TPO may be used to promote platelet increase.
Thrombocytopenia cut the spleen did not help, there may be other treatments, it is recommended to consult a doctor in time. The above medication is in accordance with the doctor’s prescription.