The main elements of the individualized treatment plan for leukemia with TCM and TCM are to use different optimal treatment plans according to the specific type of disease of the patient: (1) For subtypes with obvious advantages of TCM efficacy, such as acute promyelocytic leukemia, the use of TCM arsenic or Xiong Huang preparations, combined with TCM evidence-based treatment is the main treatment. (2) For patients with refractory leukemia who are old and frail, or who have severe damage to important organ functions and can hardly tolerate strong western medical treatment, the treatment is based on TCM evidence-based support of the righteousness and supplemented by elimination of the evil. (3) For subtypes with better efficacy of western medicine but high toxic side effects or difficult to cure, combined Chinese and Western medicine is used to reduce toxicity and increase effectiveness. At present, the Department of Hematology of the hospital is undertaking the project of “Chinese Medicine Prevention and Treatment of Major Difficult Diseases” under the National Eleventh Five-Year Plan, and the project of “Clinical Application of Chinese Medicine Intervention Treatment Plan for Refractory Acute Leukemia in the Peri-chemotherapy Period” under the National Natural Science Foundation of China. “The effect of artesunate on the proliferation of human progenitor leukemia cells and its optimal target” and other national research projects, as well as the Guangdong Provincial Science and Technology Project “Induction of BMNC-derived DC in patients with acute non-lymphoblastic leukemia in complete remission by traditional Chinese medicine “The project of Guangdong Provincial Natural Science Foundation, “Effect of artesunate on the proliferation of human primary leukemia cells and related gene expression” and other provincial and ministerial research projects; and participate in the 11th Five-Year Plan Key Specialties Collaborative Group of the State Administration of Traditional Chinese Medicine, in order to further research and explore the combination of traditional Chinese medicine and traditional Chinese and Western medicine He also participated in the 11th Five-Year Plan Collaborative Group of the National TCM Administration to further explore the better treatment plan for the prevention and treatment of acute leukemia by combining TCM and TCM.