A. Surgical treatment methods for Parkinson’s disease? 1.Destructive surgery: Due to serious adverse reactions, this approach has been basically no longer used in developed countries. 2, DBS surgery (deep brain electrical stimulation therapy): currently the best surgical treatment for Parkinson’s. 3.Stem cell transplantation: It is still in the experimental stage, and the efficacy is not yet clear. 2.What is DBS surgery (deep brain electrical stimulation therapy)? Deep brain electrical stimulation therapy uses electrodes implanted in the brain to send electrical stimulation to suppress abnormal brain nerve signals. The stimulation is delivered to precise targets related to motor control. The therapy allows Parkinson’s patients to normalize their motor functions, reduce their symptoms and improve their quality of life. Third, how effective is DBS in treating Parkinson’s disease? Clinical studies have shown that DBS for Parkinson’s disease has significant therapeutic effects: 1. It can improve patients’ symptoms such as tremor, rigidity, slow movement or inability to move, and balance disorders; 2. It can reduce the dose of oral medication; 2. It can significantly improve the quality and ability of patients’ daily life. Experience shows that the effect is significant in patients who respond well to levodopa. IV. What kind of patients are suitable for DBS surgery? 1.Patients with a clear diagnosis of primary Parkinson’s disease. 2.Patients who had good efficacy on levodopa, but now the efficacy of the drug has gradually decreased or side effects have appeared, and the disease has begun to affect normal work and life. 3. The patient has no significant intellectual impairment and is willing and able to cooperate in the surgical procedure and subsequent follow-up. v. What are the contraindications and risks of DBS surgery? DBS is a kind of surgery, so all patients with contraindications to surgery are not suitable for the surgery; DBS has certain surgical complications like other brain surgeries, but the incidence of surgical complications is low as long as the surgical indications are selected appropriately. V. Postoperative follow-up of DBS? Since Parkinson’s is a progressive disease, it is very important to follow up after DBS implantation by adjusting the stimulation frequency, pulse width and voltage to achieve the best disease control and the least side effects. Follow-up visits are 1-3 times a year for modulation testing.