Amylase in patients with severe pancreatitis is within or below the normal range, i.e. blood amylase is between 15-115 U/L using the BMD method and urine amylase is between 80-300 U/L using the Sulzer method. Because the pancreatic tissue is severely damaged in severe pancreatitis, the production of amylase will be greatly reduced, especially when the blood and urine amylase suddenly drop, it is clear that the patient is suffering from severe pancreatitis, and the patient will also have a persistent fasting blood glucose elevation, above 10 mmol/L will indicate a poor prognosis, and the serum calcium will also drop significantly, and the degree of serum calcium drop is generally parallel to the clinical severity, if the serum calcium is below 1.5 mmol/L, the patient will be able to have a prognosis. If serum calcium is below 1.5 mmol/L, the prognosis is poor. In conclusion, severe pancreatitis is a relatively dangerous disease and must be resuscitated in an intensive care ICU.