The causes of chest tightness and shortness of breath with a feeling of pressure in the chest cough include physiological and pathologic, and the pathologic factors include asthma, coronary heart disease, etc. The treatments include medications such as antiplatelet drugs and surgical treatments. Physiologic causes, such as excessive stress, mental tension, etc., can be relieved by resting and regulating emotions. 1. Physiological factors: long-term mental stress, mental tension, anxiety and depression, staying up late and not getting enough sleep, smoking and drinking and other bad habits may lead to chest tightness, shortness of breath, a feeling of pressure in the chest, coughing and other symptoms. Through active physical exercise, good habits of work and rest, and maintain a good state of mind to effectively alleviate the symptoms. 2. Pathological factors: asthma patients will have wheezing, chest tightness, cough and other symptoms. Mainly through the drug treatment such as budesonide, salbutamol and so on. At the same time to keep away from allergens. Coronary artery disease patients with myocardial ischemia leading to chest tightness with symptoms of pressure, drug treatment with aspirin, clopidogrel, etc., serious conditions can be treated by percutaneous coronary intervention and other surgical procedures. Need to choose drugs under the guidance of a doctor. There are more diseases that cause chest tightness, shortness of breath, pressure in the chest, coughing and other symptoms, such as pneumothorax, pulmonary heart disease, etc. When the patient is in discomfort, he should go to the hospital immediately. The above medications need to be used under the guidance of a physician.