Osteomyelitis of jawbone needs to be treated by medication, surgery and general measures according to the cause. 1. Medication: Doctors will give appropriate antibiotics according to the results of patients’ drug sensitivity test, so patients need to apply antibiotics such as amoxicillin, doxycycline, erythromycin, penicillin G and other antibiotics according to doctor’s instructions. For those with significant pain, non-steroidal anti-inflammatory drugs such as ibuprofen and acetaminophen can be applied. For patients with tuberculosis, anti-tuberculosis drugs such as isoniazid, rifampicin, ethambutol and streptomycin should be applied. 2. Surgery: If there is an abscess in osteomyelitis of the jaw, abscess incision should be performed. At the same time, after the inflammation subsides, surgical treatment such as tooth extraction or lesion scraping should be considered. 3. General measures: patients need to pay attention to oral hygiene, avoid eating spicy and stimulating food, pay more attention to rest, avoid exertion, and eat more food with higher nutritional value. Usually, the prognosis of osteomyelitis of the jaw is good after standardized treatment.