Fruquintinib, or furaquintinib, and hematuria on furaquintinib is a possible side effect of the drug. Hematuria after taking Furaquintinib may be an adverse drug reaction, other adverse reactions include diarrhea, nausea and vomiting, high blood pressure, and gastrointestinal bleeding. This drug is an anti-tumor drug and should be used under the guidance of a physician’s interview. It is contraindicated in patients who are allergic to this product. In addition, prostatitis, seminal vesiculitis, urinary stone disease, urinary tract infections may also cause hematuria. The appearance of hematuria can improve the urine routine, renal function, renal ultrasound, bladder ultrasound, blood routine and other related examinations to clarify the cause of the disease. The situation of hematuria after taking furaquintinib needs to be actively consulted to find the cause of the disease, in accordance with the standard treatment under the guidance of the physician’s interview, can not blindly take medication to avoid aggravating the condition.