The new coronavirus Ramada variant was first identified in Peru and has since spread rapidly across borders to multiple states, and is classified by WHO as a “variant to be observed” (VOI), which lacks uncertainty compared to Delta’s classification as a “variant of concern” and needs to be Further observations are needed. The Ramada strain has been found to cause both community transmission, clusters of transmission, and transnational transmission. What is certain is that the Ramada variant is no less active in infecting cells than the Delta variant, which is currently considered one of the most infectious strains in the world. Symptoms of infection with the Ramada strain are similar to those of the novel coronavirus, including cough, fever, loss of taste, loss of smell, body aches and shortness of breath, and studies suggest that the strain may also cause frequent gastrointestinal symptoms in patients. The mutation of the Ramada strain’s own stinger protein makes it easier for the virus to adhere to the respiratory mucosa and enter the epithelium, making it more infectious than the original neocoronavirus. In addition to being susceptible to infection, the Ramada strain also has a greater ability to resist neutralizing antibodies, probably due on the one hand to mutations in the stinger protein that have certain characteristics of evading neutralizing antibodies. On the other hand, antibodies are more difficult to neutralize because of easier access to cells. However, some studies have also indicated that the vaccine is still effective in the current situation of the Ramada strain and can greatly reduce the probability of producing severe cases, so the general public still needs to be actively vaccinated. In addition to vaccination, it is important to avoid crowded and closed public places, wear a mask when going out, and wash hands and disinfect when returning home to cut off the transmission route. If you have symptoms similar to those of the infection or have been to a medium to high risk area in the last 14 days, you should report it in a timely manner and take the initiative to isolate and follow medical advice for monitoring and other operations to prevent infection with the Ramada strain without realizing it and actively control the source of infection.