Vaginal bleeding in early pregnancy may be experienced by many people, especially patients after embryo transfer. If this is combined with abdominal pain as a symptom, it will certainly cause panic among the couple, especially the mother-to-be. Is there any danger? Do I need to go to the hospital? Do I need to take blood for ultrasound? Do I need to take medicine and injections? First of all, if intrauterine pregnancy is confirmed by ultrasound at 40 days of pregnancy, vaginal bleeding with abdominal pain is the most common symptom of pre-eclampsia, but pre-eclampsia is not equal to miscarriage, traditionally, it is mostly due to luteal insufficiency. Therefore, the effectiveness and necessity of strengthening the luteal support is controversial. In any case, in this case, the bleeding is usually small and decreasing, and the abdominal pain is relatively mild, so you can observe it temporarily, review the ultrasound regularly, pay attention to rest, don’t work too hard, and don’t catch cold and flu. If the vaginal bleeding with abdominal pain is not confirmed as intrauterine pregnancy, then the most important thing to be aware of at this time is ectopic pregnancy. In this case, a repeat ultrasound is necessary to look for the fetal sac, and if it is not found, then a repeat blood test for HCG is also necessary. In most cases, bleeding in early pregnancy is due to embryonic implantation, so there is no need to be too alarmed and observation is sufficient.