A pre-hospital examination revealed a huge tumor with a diameter of about 10 cm in the retroperitoneum. The local hospital considered the operation difficult and risky and recommended the patient to be transferred to our hospital for treatment because of his advanced age. After admission, further imaging examination revealed that the tumor was located in the posterior part of the pancreas, the lateral tumor was surrounded by the splenic artery, and the medial tumor was compressing the abdominal aorta and shifting to the right side of the spine. I made a thorough surgical plan for this complex and difficult surgery and took into account the patient’s age. The tumor was located in the lower part of the tail of the retroperitoneal pancreatic body, about 10×7×7 cm in size, hard and peritoneal, and was surrounded by many important vessels such as splenic artery and mesenteric vessels in front and around. The difficulty of freeing and revealing retroperitoneal tumor, coupled with the need for combined organ resection, often makes the operation bleeding, traumatic and difficult, which is often daunting for general surgeons. In this case, the tumor volume was huge and the patient was of advanced age. The success of the surgery was due to the careful preparation before surgery, the thorough cooperation of the anesthesia and surgery department during surgery and the fine and accurate operation during surgery.