Pregnancy is the right of every lady and the bond of family harmony and happiness. However, women of childbearing age after valve replacement surgery must pay attention: because warfarin can enter the fetus through the placenta, there is a risk of fetal malformation when warfarin is taken in the first trimester, and heparin cannot pass through the placenta, so it is generally recommended to stop taking warfarin in the first trimester and replace it with subcutaneous anticoagulation with heparin, although it is inconvenient to take the injection daily, but for the sake of your baby, please be sure to pay attention (although there are reports in the literature reports of normal babies born on warfarin). Anticoagulation treatment during abortion: If you are not suitable or do not want to continue the pregnancy, stop taking warfarin 3-5 days before the operation and operate after normal laboratory tests, or stop warfarin 5 days before the operation and inject heparin, and stop heparin 4-6 hours before the operation. Start anticoagulation 24-48 hours after postoperative bleeding stops, start anticoagulation at the original preoperative dose, and adjust warfarin dosage according to the results of the four coagulation items. Anticoagulation in the perinatal period: (1) Change warfarin to heparin 1-2 weeks before the expected date of delivery, counteract with fisetin if bleeding is high after delivery, and start oral warfarin 24-48 hours after delivery of the fetus without signs of bleeding. (2) No stopping warfarin and injecting vitamin K1 after contractions start, and start anticoagulation 24-48 hours after delivery without bleeding. (3) Treatment during cesarean section is the same as anticoagulation treatment during abortion.