Staying up late does not cause cirrhosis, cirrhosis is a chronic progressive disease, mostly due to one or more etiologies of liver damage formed by long-term or repeated action, mostly due to several years or decades of liver gradually from hepatitis, liver fibrosis progress to cirrhosis. There are many clinical causes of cirrhosis, mainly including viral hepatitis, alcoholism, nutritional disorders, industrial toxins or drugs, circulatory and metabolic disorders, etc. Viral hepatitis, especially chronic hepatitis B, is the main factor causing portal cirrhosis, and long-term heavy alcohol abuse, is also one of the main factors causing cirrhosis. Staying up late is only an occasional situation, and it is impossible to have long-term staying up late. Staying up late does cause liver damage, but it does not cause cirrhosis.