Different antihypertensive drugs have different dosage forms and different metabolic rates in the body, so the time of onset of action may also vary. Short-acting antihypertensive drugs have a faster onset of action, such as nifedipine tablets, which can generally take effect within an hour or so after taking the drug, but the maintenance time of the antihypertensive effect of this type of short-acting antihypertensive drug is relatively short, so it needs to be repeated several times a day to keep blood pressure at a stable level; for extended-release or controlled-release antihypertensive drugs, the onset of action is longer, and the maintenance time of the antihypertensive effect is also longer. For long-acting antihypertensive drugs, it is necessary to repeat the dose several times (the number of doses per day does not increase, but it is necessary to take the antihypertensive drugs regularly for several days in a row) in order to make the concentration of antihypertensive drugs in the blood reach a stable state, so as to better control blood pressure. For hypertensive patients, it is generally recommended to choose long-acting antihypertensive drugs, so that the control of blood pressure is more stable, even if you miss a long-acting antihypertensive drug, the impact on blood pressure fluctuations is not too great. Although short-acting antihypertensive drugs work faster, they tend to cause blood pressure fluctuations, especially in the case of missed doses, and blood pressure fluctuations are more pronounced. For hypertensive patients, it is advisable to choose long-acting antihypertensive drugs, and should be taken regularly on time, so as to control blood pressure more smoothly.