The difference between benign and malignant tongue root tumors is mainly manifested in the age of onset, growth rate and mode, symptoms, effects on the organism, and histological results. 1. Age of onset: benign tumors can occur at any age, while malignant tumors are more common in the elderly. 2. Growth rate and mode: benign usually grows slowly and expansively, while malignant grows faster and is mostly infiltrative. 3. Symptoms: benign ones usually have no symptoms, but malignant ones may have local pain, numbness, bleeding, and limited mouth opening. 4. Impact on the body: benign cases usually do not affect the life, but malignant cases may cause death due to malignant disease because of rapid development, metastasis, and other invasions of important organs. 5. Histology: it is the examination method to identify benign and malignant tumors accurately. The structure and morphology of benign cells are similar to normal ones, while malignant cells are poorly differentiated and heterogeneous. When tongue root tumor occurs, consult doctor in time and choose the most appropriate treatment under the guidance of professional doctors to prevent serious complications.